Taine Plumtree will start in the No. 8 jersey for just the second time in his young Test career.
South Africa lock Eben Etzebeth will lead the Sharks in the Challenge Cup final on Friday against Gloucester in place of the injured Lukhanyo Am.
Sharks head coach John Plumtree has named seven World Cup-winning South Africa internationals in his starting XV to face ASM Clermont Auvergne in the Challenge Cup semi-final on Saturday at the Twickenham Stoop.
Eben Etzebeth is set to play his first game in over two months when he starts against Ulster at Kings Park on Saturday in the United Rugby Championship.
The Sharks are set to welcome back World Cup winning South Africa centre Lukhanyo Am for their contest against Connacht at Kings Park tomorrow in the United Rugby Championship.
Zebre Parma secured a first win since April 2022 after a nail-biting 12-10 BKT United Rugby Championship victory over Hollywoodbets Sharks.
The Sharks and the Ospreys meet in a historic match at the Twickenham Stoop on Friday night, as it will be the first time a United Rugby Championship match has ever taken place in England.