Italy and Argentina have both named sides with only two players with fewer than 10 caps for their encounter in Udine on Saturday.
Defending champions Glasgow went back to the top of the BKT United Rugby Championship with a comfortable 33-3 win over Zebre at Scotstoun.
Munster legend Donncha O'Callaghan has blasted his former team following their shock to defeat to minnows Zebre Parma in Round 2 of the URC.
Zebre Parma made history by securing their first-ever victory over Munster with a 42-33 bonus-point win in the United Rugby Championship.
Italy head coach Gonzalo Quesada has announced a preliminary squad of 39 players for a training camp in L'Aquila from 19 to 22 June, in preparation for the 2024 summer tour.
Scotland fly-half Adam Hastings has returned to the Gloucester squad to face Benetton on Saturday in the Challenge Cup semi-final at Kingsholm after missing the loss to Exeter Chiefs last week in the Gallagher Premiership.
Montpellier Herault second-row Paul Willemse has received a suspension after an independent Disciplinary Hearing related to his actions in the EPCR Challenge Cup, Round of 16 match against Ulster Rugby at GGL Stadium last weekend.
Italy have made three changes from the team that defeated Scotland last weekend for their Wooden Spoon decider against Wales at the Principality Stadium on Saturday in round five of the Guinness Six Nations.
Harlequins winger Louis Lynagh is set to make his Italy debut on Saturday in round four of the Guinness Six Nations as head coach Gonzalo Quesada has made three changes from the XV that drew with France in round three.
