France's uncapped duo of Joshua Brennan and Regis Montagne have dropped out of their 42-man squad as they prepare to face Japan on Saturday at the Stade de France.
France have sent 19 players back to their clubs for the next round of Top 14 action this weekend.
Antoine Dupont has returned to the France XVs squad after missing the first half of 2024 as he focussed on his ultra-successful switch to sevens.
Fabian Galthie's baby-faced assassins put behind them a challenging week off the pitch to push an experienced Argentinean side in Buenos Aires. Snatching the lead early in the second half following a furious comeback, Les Bleus looked set to complete a first series win in Argentina since 1998.
A youthful France side came away from Mendoza with a 28-13 win over an uninspired Argentina side on Saturday in what was the Pumas' first match under new coach Felipe Contepomi.
Les Bleus had won the 2018 and 2019 tournament finals in Beziers and Rosario but the pandemic forced the cancellation of the next three tournaments before it returned in 2023.
Fabien Galthie has named a 32-player initial France squad that will assemble at their Marcoussis training base this week, 19 of which are uncapped.
Portugal star Nicolás Martins has signed for Top 14 strugglers Montpellier, and will be under the command of director of rugby Bernard Laporte from July until 2026.
Five up-and-coming youngsters will fill in for them at national team training.
Perpignan's 19-year-old lock Posolo Tuilagi is set to receive his first call-up into the France senior squad this week alongside two other U20 world champions, according to French outlet Midi Olympique.