For the second time in two years USA Rugby will get a chance to take on arguably their most frustrating opponent on the international stage.
Vince and Manu Tshituka's origin tale is one of war, love and triumph against the odds.
Toulouse have selected four members of France's 34-player squad in their team to play Castres on Saturday in the Top 14, including second row duo Thibaud Flament and Emmanuel Meafou.
Is Robbie Henshaw set for the British and Irish Lions 13 jersey? Or has competition arisen that could deny him that Test starters spot?
The match will see the return to action of Jaco Kriel, who left Premiership side Gloucester at the start of the year to return to SA and the Lions earlier this year.
Johannesburg side, the Lions, arrived back in South Africa from New Zealand on Sunday and have gone into self-isolation for 14 days.
There are four changes to the Stormers starting line-up to take on the Lions in Johannesburg on Saturday while the Lions had made just a single change to their starting side.
Elton Jantjies will lead the Emirates Lions on the field for the first time in their Super Rugby opener against the Jaguares in Argentina this weekend.
The loss of almost 50 caps worth of Test experience may not sound that dramatic, but becomes more pronounced when you look at the Super Rugby experience that departed the Lions.