Ford will celebrate his 32nd birthday next March and is now in the final year of his contract with Sale Sharks.
Harlequins have been forced into a late change with England prop Joe Marler being withdrawn from the matchday team.
England and British and Irish Lions fly-half Marcus Smith will make his first start for Harlequins after missing last week's Gallagher Premiership Round 2 loss to Saracens.
Harlequins have confirmed a 68-man senior squad - consisting of 43 senior players and bolstered by 25 from the club’s senior academy - for the upcoming 2022/23 season.
The Premiership season is drawing to a close which means numerous players are getting ready to join new clubs over the summer break. Plenty of transfers have already been confirmed across the league.
Saracens have made 13 changes to their XV for this Saturday’s Gallagher Premiership semi-final at home to defending champions Harlequins, who have changed just two of their for the playoff fixture. Mark MacCall’s team were hammered 54-7 last Saturday.
Gallagher Premiership champions Harlequins have made just one change to their team to face Montpellier in this Saturday's Heineken Champions Cup rematch in London, Will Evans coming into the XV at openside in place of Tom Lawday.
Harlequins have confirmed the 44-man senior squad set to compete for the remainder of the current season.
Matas Jurevicius was a regular starter for London Scottish before their Championship campaign was curtailed by the coronavirus pandemic.