Veteran scrum-half Conor Murray has returned home to Ireland midway through Munster's tour of South Africa for personal reasons.
The veteran back-rower and tighthead Oli Jager were starters in last Saturday’s rain-sodden win over Ospreys.
World Cup-winning Springbok Jean Kleyn is poised to make his return to action for the first time since November last year after recovering from an eye injury.
Munster player ratings: The men in red have catastrophically fumbled what should have been a routine win against a plucky Northampton Saints side who found a way to win despite being down to 14 men for much of the contest.
Munster have named their team to host Leinster in the sold out URC Interpro derby on St Stephen's Day, Tuesday December 26.
Ulster will be boosted on Friday by the return of some of their World Cup players for their clash against United Rugby Championship winners Munster at the Kingspan Stadium.
Springboks lock RG Snyman is poised to start his first Munster match since his injury-ruined debut for the club in August 2020.
Munster showed no mercy as Gavin Coombes’ hat-trick of tries inspired a thumping 58-3 win over an off-colour Ospreys in their United Rugby Championship clash at Thomond Park.
The 31-year-old Munster player was due to undergo surgery on Thursday.