The Lions' unbeaten start to the season came to an abrupt end this afternoon as they fell 24 - 6 to Leinster at the Aviva Stadium.
Despite the Lions having lock Ruben Schoeman red-carded after 26 minutes, they claimed a bonus-point victory.
Leinster moved four points clear at the top of the United Rugby Championship following a 21-13 win over the Lions at the RDS Arena.
The Bulls made it back-to-back United Rugby Championship wins over the Lions with a 21-13 victory in Pretoria.
The Scarlets secured their first victory of the United Rugby Championship with a 36-13 bonus-point win over the Lions in Llanelli.
The match will see the return to action of Jaco Kriel, who left Premiership side Gloucester at the start of the year to return to SA and the Lions earlier this year.
There are four changes to the Stormers starting line-up to take on the Lions in Johannesburg on Saturday while the Lions had made just a single change to their starting side.
Elton Jantjies will lead the Emirates Lions on the field for the first time in their Super Rugby opener against the Jaguares in Argentina this weekend.
